Home Business Wire Twist Bioscience Reports Fiscal Third Quarter 2022 Financial Results

Twist Bioscience Reports Fiscal Third Quarter 2022 Financial Results

— Record revenue of $56.1M in 3QFY22; Increase of 60% over $35.0M in Fiscal 2021 —

— Orders increased 53% in 3QFY22 over fiscal 2021 to $59.7M —

— Increases revenue guidance to $203 million for full year fiscal 2022 —

SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today reported financial results and business highlights for the third quarter of fiscal 2022 ended June 30, 2022.

We are the high quality, low cost leader and as the macroeconomic environment continues to hold uncertainty, Twist’s product offerings are resonating with customers,” said Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience. “We continue to see large accounts expanding their footprint while we also focus on diversifying our risk across an increasing number of customers, particularly in biopharma. We entered into our first exclusive option and license agreement for a Twist-discovered antibody and continue to build a robust ecosystem for DNA data storage through educational materials, including the most recently published white paper, and by driving toward an interoperable system through the development of industry standards.”

Dr. Leproust continued, “Moving forward, we plan to launch the Factory of the Future in January 2023, which will facilitate growth across all areas of our business. We are well positioned to take market share in synbio and NGS, deliver new antibody targets for our biopharma customers and advance our efforts in DNA data storage toward our first commercial solution, all while targeting toward adjusted EBITDA breakeven at $300 million annual revenue for the core business.”

FISCAL 2022 THIRD QUARTER FINANCIAL RESULTS

  • Orders: Total orders received for the third quarter of fiscal 2022 were $59.7 million compared to $39.1 million for the same period of fiscal 2021.
  • Revenue: Total revenues for the third quarter of fiscal 2022 were $56.1 million compared to $35.0 million for the same period of fiscal 2021.
  • Cost of Revenues: Cost of revenues for the third quarter of fiscal 2022 was $31.0 million compared to $20.9 million for the same period of fiscal 2021.
  • Research and Development Expenses: Research and development expenses for the third quarter of fiscal 2022 were $36.8 million compared to $19.8 million for the same period of fiscal 2021.
  • Selling, General and Administrative Expenses: Selling, general and administrative expenses for the third quarter of fiscal 2022 were $53.7 million compared to $34.5 million for the same period of fiscal 2021.
  • Net Loss: Net loss attributable to common stockholders for the third quarter of fiscal 2022 was $60.5 million, or $1.08 per share, compared to $40.0 million, or $0.82 per share, for the same period of fiscal 2021.
  • Cash Position: As of June 30, 2022, the company had $527.6 million in cash, cash equivalents and investments.

Recent Highlights:

SynBio and NGS

  • Shipped products to approximately 1,900 customers in the third quarter of fiscal 2022, versus approximately 1,800 in the third quarter of fiscal 2021.
  • Shipped approximately 163,000 genes during the third quarter of fiscal 2022, compared with approximately 107,000 in the third quarter of fiscal 2021.
  • Launched two human monkeypox synthetic DNA controls, expanding Twist’s portfolio of synthetic controls and reference standards.
  • Offered two new SARS-CoV-2 controls for the BA.2.12.1 sublineage of the omicron variant.
  • Received expanded Emergency Use Authorization from the U.S. Food and Drug Administration for the SARS-CoV-2 Next-Generation Sequencing (NGS) Assay developed with Biotia for the qualitative detection, identification and differentiation of SARS-CoV-2 lineages and identification of specific genomic mutations.
  • Launched Twist MRD Rapid 500 Panel to enable customers to implement fully customizable panels for $50 per sample.
  • Launched the Twist Human Methylome Panel covering 84.2% of GpC islands to support the discovery of differentially methylated regions and epigenetic target identification for cancer metastasis and human development research.
  • Entered into a collaboration with DNAnexus to integrate DNAnexus’ biomedical data analysis platform with Twist’s NGS Methylation Detection and Unique Molecular Identifier Adapter Systems.

BioPharma and DNA Data Storage

  • Entered into a research, exclusive option and license agreement with Astellas for a Twist-discovered antibody targeting an undisclosed checkpoint inhibitor.
  • Entered into a collaboration with Ildong Pharmaceutical, Twist’s first collaboration with a South Korea-based company, under which Ildong will license a suite of Twist VHH antibody libraries to use to discover and develop antibodies for applications in immuno-oncology.
  • Entered into an antibody discovery agreement with Xilio Therapeutics to advance the development of novel immunotherapies.
  • Hosted a ribbon-cutting ceremony for the new location of Twist Boston, also known as Abveris, in Quincy, MA.
  • The DNA Data Storage Alliance joined SNIA as a Technology Affiliate group to accelerate its mission to create an interoperable ecosystem for DNA-based data storage solutions.
  • Participated in panels and presentations at key data storage and industry conferences including Fujifilm’s 12th Annual Global IT Executive Summit, the 2022 MRS Spring Meeting and Exhibit, and the Flash Memory Summit.
  • Highlighted a DNA data storage white paper that quantifies the need for new storage mediums to address the zone of potential insufficiency where current methods of storing data, even when scaled, will not meet future demand.

Updated Fiscal 2022 Financial Guidance

The following statements are based on Twist’s current expectations for fiscal 2022. The following statements are forward-looking, and actual results could differ materially depending on market conditions and the factors set forth under “Forward-Looking Statements” below.

For the full fiscal year 2022, Twist provided the following updated financial guidance:

  • Revenue is now expected to be approximately $203 million, an increase from previous guidance of $191 million to $199 million
    • SynBio revenue including Ginkgo Bioworks is expected to be $80 million, an increase from previous guidance of $71 million to $73 million
    • NGS revenue is estimated to be approximately $97 million, an increase from previous guidance of $94 million to $96 million
    • Biopharma revenue is estimated to be approximately $26 million, at the low end of the previous guidance range of $26 million to $30 million
  • Gross margin is expected to be 40% for fiscal 2022
  • Operating expenses including R&D and SG&A are expected to be approximately $330 million for the year
  • Net loss is expected to be approximately $250 million, reflecting the impact of the Abveris acquisition in stock-based compensation and includes:
    • R&D expense is expected to be approximately $125 million, a decrease from previous guidance of $130 million
      • Approximately $40 million of R&D expense is expected to be for DNA data storage
    • Stock-based compensation is expected to be approximately $80 million
    • Depreciation is expected to be $14 million
    • Capital expenditures are expected to be in the range of $95 to $100 million, including building out the “Factory of the Future”

Conference Call Information

The company plans to hold a conference call and live audio webcast for analysts and investors at 8:00 a.m. Eastern Time today to discuss its financial results and provide an update on the company’s business. The conference call will be webcast live through the Investor Relations section under the “Company” tab at www.twistbioscience.com. Those parties interested in participating via telephone must register on the Company’s Investor Relations website or by clicking here. Upon registration, all telephone participants will receive the dial-in number along with a unique PIN number that can be used to access the call. To avoid delays, we encourage participants to dial into the conference call fifteen minutes ahead of the scheduled start time. The webcast replay will be available for two weeks.

About Twist Bioscience

Twist Bioscience is a leading and rapidly growing synthetic biology and genomics company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Twist is leveraging its unique technology to manufacture a broad range of synthetic DNA-based products, including synthetic genes, tools for next-generation sequencing (NGS) preparation, and antibody libraries for drug discovery and development. Twist is also pursuing longer-term opportunities in digital data storage in DNA and biologics drug discovery. Twist makes products for use across many industries including healthcare, industrial chemicals, agriculture and academic research.

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Legal Notice Regarding Forward-Looking Statements

This press release contains forward-looking statements. All statements other than statements of historical facts contained herein are forward-looking statements reflecting the current beliefs and expectations of management made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including, but not limited to, projections under the heading “Updated Fiscal 2022 Financial Guidance,” statements regarding future growth and expansion, estimated annual revenues to achieve EBITDA break-even point and Twist Bioscience’s other expectations regarding its future operations plans and financial performance, introduction of new products, and newly announced partnerships. Forward-looking statements involve known and unknown risks, uncertainties, and other important factors that may cause Twist Bioscience’s actual results, performance, or achievements to be materially different from any future results, performance, or achievements expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others, the risks and uncertainties of the duration, extent and impact of the COVID-19 pandemic, including any reductions in demand for our products (or deferred or canceled orders) globally or in certain regions; the ability to attract new customers and retain and grow sales from existing customers; risks and uncertainties of rapidly changing technologies and extensive competition in synthetic biology that could make the products Twist Bioscience is developing obsolete or non-competitive; uncertainties of the retention of significant customers; the ability of Twist Bioscience to successfully integrate acquired companies, including Abveris, and to achieve expected benefits from acquisitions; supply chain and other disruptions caused by the COVID-19 pandemic or otherwise; risks of third party claims alleging infringement of patents and proprietary rights or seeking to invalidate Twist Bioscience’s patents or proprietary rights; and the risk that Twist Bioscience’s proprietary rights may be insufficient to protect its technologies. For a description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Twist Bioscience’s business in general, see Twist Bioscience’s risk factors set forth in Twist Bioscience’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 6, 2022 and subsequent filings with the SEC. Any forward-looking statements contained in this press release speak only as of the date hereof, and Twist Bioscience specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.

Twist Bioscience Corporation

Condensed Consolidated Statements of Operations

(Unaudited)

(in thousands)

 

 

Three months ended

June 30,

Nine months ended

June 30,

(In thousands, except per share data)

2022

2021

2022

2021

Revenues

$

56,113

 

$

35,018

 

$

146,259

 

$

94,382

 

Operating expenses:

 

 

 

 

Cost of revenues

$

30,974

 

$

20,933

 

$

87,744

 

$

58,123

 

Research and development

 

36,840

 

 

19,838

 

 

90,701

 

 

49,629

 

Selling, general and administrative

 

53,693

 

 

34,478

 

 

158,790

 

 

97,658

 

Change in fair value of contingent considerations and holdbacks

 

(4,231

)

 

1,887

 

 

(13,071

)

 

1,887

 

Total operating expenses

$

117,276

 

$

77,136

 

$

324,164

 

$

207,297

 

Loss from operations

$

(61,163

)

$

(42,118

)

$

(177,905

)

$

(112,915

)

Interest income

 

722

 

 

86

 

 

1,134

 

 

377

 

Interest expense

 

 

 

(70

)

 

(54

)

 

(284

)

Other income (expense), net

 

(225

)

 

(312

)

 

(626

)

 

(305

)

Benefit from (provision for) income taxes

 

149

 

 

2,377

 

 

10,703

 

 

2,271

 

Net loss attributable to common stockholders

$

(60,517

)

$

(40,037

)

$

(166,748

)

$

(110,856

)

Net loss per share attributable to common stockholders—basic and diluted

$

(1.08

)

$

(0.82

)

$

(3.15

)

$

(2.32

)

Weighted average shares used in computing net loss per share attributable to common stockholders—basic and diluted

 

56,287

 

 

48,963

 

 

53,005

 

 

47,881

 

Twist Bioscience Corporation

Condensed Consolidated Balance Sheets

(Unaudited)

(in thousands)

 

(In thousands)

June 30,
2022

September 30,
2021

Assets

 

 

Current assets:

 

 

Cash and cash equivalents

$

376,249

$

465,829

Short-term investments

 

151,342

 

12,034

Accounts receivable, net

 

41,195

 

28,549

Inventories

 

43,022

 

31,800

Prepaid expenses and other current assets

 

12,309

 

8,283

Total current assets

$

624,117

$

546,495

Property and equipment, net

 

127,011

 

44,122

Operating lease right-of-use assets

 

76,165

 

61,580

Other non-current assets

 

152,370

 

49,900

Total assets

$

979,663

$

702,097

Liabilities and stockholders’ equity

 

 

Current liabilities:

 

 

Accounts payable

$

21,014

$

14,900

Accrued expenses

 

9,499

 

6,437

Accrued compensation

 

27,698

 

22,327

Current portion of operating lease liability

 

14,352

 

8,213

Current portion of long-term debt

 

 

1,552

Other current liabilities

 

20,123

 

9,623

Total current liabilities

$

92,686

$

63,052

Operating lease liability, net of current portion

 

64,244

 

53,156

Other non-current liabilities

 

2,056

 

5,068

Total liabilities

$

158,986

$

121,276

Total stockholders’ equity

$

820,677

$

580,821

Total liabilities and stockholders’ equity

$

979,663

$

702,097

 

Contacts

Angela Bitting

SVP, Corporate Affairs

Twist Bioscience

abitting@twistbioscience.com

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